JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies

NDC80 Antibody

SKU : BHA10559237

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA215188
Alternative Names	HEC1; HEC; Highly expressed in cancer; rich in leucine heptad repeats; KNTC2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.Chen Y., Mol. Cell. Biol. 17:6049-6056(1997).The MGC Project Team, Genome Res. 14:2121-2127(2004).Zheng L., Mol. Cell. Biol. 19:5417-5428(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human KNTC2.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Chen Y., Mol. Cell. Biol. 17:6049-6056(1997). The MGC Project Team, Genome Res. 14:2121-2127(2004). Zheng L., Mol. Cell. Biol. 19:5417-5428(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total KNTC2 protein.
Subcellular Location	Nucleus, Chromosome, centromere, kinetochore

Uniprot	O14777
Database Links	HGNC:16909 OMIM:607272 KEGG:hsa:10403 STRING:9606.ENSP00000261597 UniGene:Hs.414407
Function	Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity
Protein Families	NDC80/HEC1 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10559237	CSB-PA215188	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.