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Home / Antibodies

NCAPH Antibody

SKU : BHA10558358

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA995479
Alternative Names	Condensin complex subunit 2; Non-SMC condensin I complex subunit H; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.Nomura N., DNA Res. 1:223-229(1994).The MGC Project Team; Genome Res. 14:2121-2127(2004).Cabello O.A., Mol. Biol. Cell 12:3527-3537(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human NCAPH.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Nomura N., DNA Res. 1:223-229(1994). The MGC Project Team; Genome Res. 14:2121-2127(2004). Cabello O.A., Mol. Biol. Cell 12:3527-3537(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total NCAPH protein.
Subcellular Location	Nucleus, Cytoplasm, Chromosome

Uniprot	Q15003
Database Links	HGNC:1112 OMIM:602332 KEGG:hsa:23397 STRING:9606.ENSP00000240423 UniGene:Hs.308045
Function	Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Protein Families	CND2 (condensin subunit 2) family
Tissue Specificity	Widely expressed at low level. Expressed in proliferating cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558358	CSB-PA995479	100ul	$297		Add to Cart

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