Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid(3+) into the less toxic dimethylarsonic acid.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid.
Host
Rabbit
Immunogen
N-6 adenine-specific DNA methyltransferase 1(putative)
Isotype
IgG
Molecular Weight
23kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
C21orf127, HEMK2
Antigen
N6AMT1
Uniprot
Q9Y5N5
Gene Id
29104
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)