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Home / Antibodies

N4BP1 Antibody

SKU : BHA10558529

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA620222
Alternative Names	Nedd4 binding protein 1; NEDD4-binding protein 1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates By similarity.Ishikawa K., DNA Res. 5:169-176(1998).The MGC Project Team; Genome Res. 14:2121-2127(2004).Matsuoka S., Science 316:1160-1166(2007).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human N4BP1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates By similarity. Ishikawa K., DNA Res. 5:169-176(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004). Matsuoka S., Science 316:1160-1166(2007).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total N4BP1 protein.
Subcellular Location	Nucleus, nucleolus, Nucleus, PML body

Uniprot	O75113
Database Links	HGNC:29850 KEGG:hsa:9683 STRING:9606.ENSP00000262384 UniGene:Hs.511839
Function	Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).
Protein Families	N4BP1 family
Tissue Specificity	Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558529	CSB-PA620222	100ul	$297		Add to Cart

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