Mouse Anti-Human Myosin heavy chain Monoclonal IgG1

Mfr.No.	SMC-258, SMC-258D, SMC-258D-A390, SMC-258D-A488, SMC-258D-A594, SMC-258D-BI, SMC-258D-FITC
Immunogen Species	Human
Alternative Names	Cellular myosin heavy chain Antibody, Cellular myosin heavy chain type B Antibody, MYH 10 Antibody, Myosin 10 Antibody, Myosin heavy chain 10 Antibody, Myosin heavy chain non muscle 11b Antibody, Myosin-10 Antibody, Non muscle myosin heavy chain B Antibody
Categories	Antibodies
Cellular Localization	Cell projection, Lamellipodium
Certificate Of Analysis	A 1:100 dilution of SMC-258 was sufficient for detection of Myosin heavy chain in Nenmatodes using Goat Anti-Mouse IgG as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Human Myosin heavy chain Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	A synthesized peptide derived from human Myosin Heavy Chain, Homo Sapiens (Human)
Immunogen Region	A synthesized peptide derived from human Myosin Heavy Chain
Isotype	IgG1
Launch Date	2016/09/06
Net Weight (g)	0.1
Reactivity	Fruit Fly, Rat, Mouse, Human, Nematode
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Drosophila, C. elegans, Human

Swissprot	P35580
Accession Number	NP_005955.3
Gene Id	4628
Target	Myosin heavy chain
Clone No	11C2
Research Area	Cell Signaling, Microfilaments, Myosin, Immunology, Autoimmune, Cardiovascular System, Heart, Contractility, Cytoskeleton

Buffer	PBS (without Mg2+ and Ca2+), 50% glycerol, pH 7.4, 150mM NaCl, 0.02% sodium azide
Dilutions	IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Scientific Background	Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other motility processes in eukaryotes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~220kDa, endogenous MHC proteins.
Storage	-20ºC
Storage Buffer	PBS (without Mg2+ and Ca2+), 50% glycerol, pH 7.4, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, ICC/IF
Description	IHC ; ICC ; IF
Dilution	IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Pollard TD et al. (1973) The Journal of Biological Chemistry. 248 (13): 468290.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11902219-1	SMC-258D	Unconjugated	100 ul	$286	Add to Cart
BHA11902219-2	SMC-258D-A390	ATTO 390	100 ul	$340	Add to Cart
BHA11902219-3	SMC-258D-A488	ATTO 488	100 ul	$339	Add to Cart
BHA11902219-4	SMC-258D-A594	ATTO 594	100 ul	$339	Add to Cart
BHA11902219-5	SMC-258D-BI	Biotin	100 ul	$334	Add to Cart
BHA11902219-6	SMC-258D-FITC	FITC	100 ul	$330	Add to Cart

Myosin heavy chain Antibody, Clone 11C2 - SMC-258