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Home / Primary Antibodies

MYO9B Antibody

SKU : BHA10558515

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA273051
Alternative Names	Myosin-Ixb; Unconventional myosin-9b;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho.Wirth J.A., J. Cell Sci. 109:653-661(1996).Grewal P.K., Gene 240:389-398(1999).Post P.L., J. Cell Sci. 111:941-950(1998).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human MYO9B.
Involvement In Disease	Celiac disease 4 (CELIAC4)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho. Wirth J.A., J. Cell Sci. 109:653-661(1996). Grewal P.K., Gene 240:389-398(1999). Post P.L., J. Cell Sci. 111:941-950(1998).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MYO9B protein.
Subcellular Location	Cytoplasm, cell cortex, Cytoplasm, perinuclear region, Cytoplasm, cytoskeleton

Uniprot	Q13459
Database Links	HGNC:7609 OMIM:602129 KEGG:hsa:4650 STRING:9606.ENSP00000380444 UniGene:Hs.123198
Function	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions
Protein Families	TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
Tissue Specificity	Detected in peripheral blood leukocytes (at protein level) (PubMed:9490638). Expressed predominantly in peripheral blood leukocytes and at lower levels, in thymus, spleen, testis, prostate, ovary, brain, small intestine and lung.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558515	CSB-PA273051	100ul	$297		Add to Cart

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