Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases.
Formulation
1 mg/ml in 1X PBS; BSA free, sodium azide free
Host
Mouse
Immunogen Region
A synthetic peptide from the C terminal region of the human protein was used as the immunogen for the Myelin PLP antibody. The epitope has been mapped to amino acids GRGTKF.
Isotype
Mouse IgG2a
Species Reactivity
Human
Note
Optimal dilution of the Myelin PLP antibody should be determined by the researcher.
Uniprot
P60201
Format
Purified
Purity
Protein G affinity chromatography
Storage
Store the Myelin PLP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Applications
IHC-P
Description
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT