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Home / Primary Antibodies

MyD88 Antibody (R32812)

SKU : BHA17106107

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NSJ Bioreagents

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Mfr.No.	R32812
Clonality	Polyclonal
Description	MYD88 (Myeloid differentiation primary response gene 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	A recombinant rat protein corresponding to amino acids D14-D263 was used as the immunogen for the MyD88 antibody.
Isotype	IgG
Predicted Reactivity	Rat
Reactivity	Rat
Recombinant	No

Uniprot	Q6Y1S1

Buffer	Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the MyD88 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Dilution	Weste Blot: 0.5-1ug/ml,ELISA (Capture; recombinant rat protein): 0.1-0.5ug/ml (BSA-free formulation available)

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17106107	R32812	100 ug	$419		Add to Cart

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