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Home / Antibodies

MUC1 Antibody / Mucin-1 (V3697SAF)

SKU : BHA17125474

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NSJ Bioreagents

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Mfr.No.	V3697SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	Human milk fat globule membranes were used as the immunogen for this recombinant Mucin-1 antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Titration of the recombinant Mucin-1 may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	P15941

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant Mucin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125474	V3697SAF-100UG	100 ug	$499		Add to Cart

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