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Home / Primary Antibodies

MRPL3 Antibody

SKU : BHA10558497

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA553771
Alternative Names	39S ribosomal protein L3; mitochondrial; L3mt; mitochondrial 60S ribosomal protein L3; mitochondrial ribosomal protein L3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.Ou J.-H., Nucleic Acids Res. 15:8919-8934(1987).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Burkard T.R., BMC Syst. Biol. 5:17-17(2011).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human MRPL3.
Involvement In Disease	Combined oxidative phosphorylation deficiency 9 (COXPD9)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. Ou J.-H., Nucleic Acids Res. 15:8919-8934(1987). Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Burkard T.R., BMC Syst. Biol. 5:17-17(2011).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MRPL3 protein.
Subcellular Location	Mitochondrion

Uniprot	P09001
Database Links	HGNC:10379 OMIM:607118 KEGG:hsa:11222 STRING:9606.ENSP00000264995 UniGene:Hs.205163
Protein Families	Universal ribosomal protein uL3 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558497	CSB-PA553771	100ul	$297		Add to Cart

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