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Home / Antibodies

MRPL10 Antibody

SKU : BHA10558158

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA982191
Alternative Names	l10mt; mgc17973; mitochondrial ribosomal protein l10; mrp-l10; mrp-l8
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.The MGC Project Team; Genome Res. 14:2121-2127(2004).Kenmochi N., Genomics 77:65-70(2001).Koc E.C., J. Biol. Chem. 276:43958-43969(2001)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MRPL10.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. The MGC Project Team; Genome Res. 14:2121-2127(2004). Kenmochi N., Genomics 77:65-70(2001). Koc E.C., J. Biol. Chem. 276:43958-43969(2001)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MRPL10 protein.
Subcellular Location	Mitochondrion

Uniprot	Q7Z7H8
Database Links	HGNC:14055 OMIM:611825 KEGG:hsa:124995 STRING:9606.ENSP00000290208 UniGene:Hs.347535
Protein Families	Universal ribosomal protein uL10 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558158	CSB-PA982191	100ul	$297		Add to Cart

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