Max-binding protein MNT; Protein ROX; Myc antagonist MNT; MNT; ROX
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.Sugano S., Nat. Genet. 36:40-45(2004).Venter J.C., Submitted (SEP-2005).Mann M., Mol. Cell 31:438-448(2008).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human MNT.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Sugano S., Nat. Genet. 36:40-45(2004). Venter J.C., Submitted (SEP-2005). Mann M., Mol. Cell 31:438-448(2008).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total MNT protein.
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Pathway
Excitatory synapse pathway
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.