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Home / Primary Antibodies

MN1 Antibody

SKU : BHA10557908

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA783625
Alternative Names	Probable tumor suppressor protein MN1; MN1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in tumor suppression.Deprez R.H.L., Oncogene 10:1521-1528(1995).The MGC Project Team, Genome Res. 14:2121-2127(2004).Dmitrenko V.V., Cyt. Genet. (Russ.) 30:41-47(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MN1.
Involvement In Disease	A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with ETV6.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	May play a role in tumor suppression. Deprez R.H.L., Oncogene 10:1521-1528(1995). The MGC Project Team, Genome Res. 14:2121-2127(2004). Dmitrenko V.V., Cyt. Genet. (Russ.) 30:41-47(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MN1 protein.

Uniprot	Q10571
Database Links	HGNC:7180 OMIM:156100 KEGG:hsa:4330 STRING:9606.ENSP00000304956 UniGene:Hs.268515
Function	Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable).
Tissue Specificity	Ubiquitously expressed. Highest levels in skeletal muscle.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557908	CSB-PA783625	100ul	$297		Add to Cart

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