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Home / Antibodies

MMP3 Antibody / Matrix Metalloproteinase 3 (V7960SAF)

SKU : BHA17127094

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NSJ Bioreagents

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Mfr.No.	V7960SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 317-327 from the human protein were used as the immunogen for this Matrix Metalloproteinase 3 antibody.
Isotype	Mouse IgG1, lambda
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P08254

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Matrix Metalloproteinase 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA: 2-4ug/ml for coating (order BSA/azide-free format)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/matrix-metalloproteinase-3-antibody-1b4-v7960" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127094	V7960SAF-100UG	100 ug	$499		Add to Cart

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