MMP1 Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. Belongs to the peptidase M10A family.
Host
Rabbit
Immunogen
A synthesized peptide derived from Human MMP1
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
MMP1 Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. Belongs to the peptidase M10A family.
Species
Homo Sapiens (Human)
Specificity
MMP1 antibody detects endogenous levels of total MMP1