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Home / Antibodies

MLLT10 Antibody

SKU : BHA10557883

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA578091
Alternative Names	Protein AF-10; MLLT10; AF10;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.Chaplin T., Blood 85:1435-1441(1995).Deloukas P., Nature 429:375-381(2004).Matsuoka S., Science 316:1160-1166(2007).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human AF10.
Involvement In Disease	A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein.; DISEASE: Note=A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. Chaplin T., Blood 85:1435-1441(1995). Deloukas P., Nature 429:375-381(2004). Matsuoka S., Science 316:1160-1166(2007).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total AF10 protein.
Subcellular Location	Nucleus

Uniprot	P55197
Gene Id	8028
Database Links	HGNC:16063 OMIM:602409 KEGG:hsa:8028 STRING:9606.ENSP00000307411 UniGene:Hs.30385
Function	Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.
Tissue Specificity	Expressed abundantly in testis.
Weight	20,047 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557883	CSB-PA578091	100ul	$297		Add to Cart

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