Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.Kvasha S., Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.Nagase T., DNA Res. 8:85-95(2001).Gregory S.G., Nature 441:315-321(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human MAP3KL4.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Kvasha S., Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. Nagase T., DNA Res. 8:85-95(2001). Gregory S.G., Nature 441:315-321(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total MAP3KL4 protein.