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Home / Primary Antibodies / Monoclonal Antibodies

Mitofusin 2 Antibody, Clone S153-5 - SMC-457

BHA11904590
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Swissprot Q80U63
Accession Number NP_573464.2
Gene Id 170731
Target Mitofusin 2
Clone No S153-5
Research Area Cell Signaling, Neurodegeneration, Cell Markers, Cancer, Apoptosis, Neuroscience
Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~90kDa. No cross-reactivity against Mitofusin-1.
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11904590-1 SMC-457D Unconjugated 100 ug $330
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BHA11904590-2 SMC-457D-A390 ATTO 390 100 ug $384
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BHA11904590-3 SMC-457D-A488 ATTO 488 100 ug $383
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BHA11904590-4 SMC-457D-A594 ATTO 594 100 ug $383
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BHA11904590-5 SMC-457D-ALP Alkaline Phosphatase 100 ug $376
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BHA11904590-6 SMC-457D-APC APC 100 ug $382
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BHA11904590-7 SMC-457D-BI Biotin 100 ug $378
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BHA11904590-8 SMC-457D-FITC FITC 100 ug $374
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BHA11904590-9 SMC-457D-HRP HRP 100 ug $370
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BHA11904590-10 SMC-457D-PCP PerCP 100 ug $382
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BHA11904590-11 SMC-457D-RPE RPE 100 ug $380
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BHA11904590-12 SMC-457S Unconjugated 12 ug $44
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