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Home / Antibodies

MIA2 Antibody

SKU : BHA10558481

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA056159
Alternative Names	Melanoma inhibitory activity protein 2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage.Bosserhoff A.K., J. Biol. Chem. 278:15225-15231(2003).Heilig R., Nature 421:601-607(2003).Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MIA2.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. Bosserhoff A.K., J. Biol. Chem. 278:15225-15231(2003). Heilig R., Nature 421:601-607(2003). Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MIA2 protein.
Subcellular Location	Isoform 1: Endoplasmic reticulum membrane, Single-pass membrane protein

Uniprot	Q96PC5
Database Links	HGNC:18432 OMIM:608001 KEGG:hsa:4253 STRING:9606.ENSP00000280082 UniGene:Hs.287694
Function	Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum
Protein Families	MIA/OTOR family
Tissue Specificity	Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis (PubMed:12586826). Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney,

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558481	CSB-PA056159	100ul	$297		Add to Cart

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