G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 681-715 from human GRM2 was used as the immunogen for the mGluR2 antibody.
Isotype
Ig
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
Q14416
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
Aliquot the mGluR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.