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Home / Primary Antibodies

METTL14 Antibody (N-Terminal Region) (F54217)

SKU : BHA17102729

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NSJ Bioreagents

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Mfr.No.	F54217, F54217-0.05ML, F54217-0.2ML
Clonality	Polyclonal
Description	N6-adenosine-methyltransferase subunit METTL14 is an N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-(AG)GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 2-36 from the N-terminal region of the human protein was used as the immunogen for the METTL14 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	Q9HCE5

Format	Antigen affinity purified
Purification	Peptide affinity purified
Storage	Aliquot the METTL14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Weste Blot: 1:2000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102729-1	F54217-0.05ML	0.05ml	$165		Add to Cart
BHA17102729-2	F54217-0.2ML	0.2ml	$379		Add to Cart

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