Rabbit Anti-Human Met (pThr1241) Polyclonal

Mfr.No.	SPC-1021, SPC-1021D, SPC-1021D-A390, SPC-1021D-A488, SPC-1021D-A594, SPC-1021D-BI, SPC-1021D-FITC
Immunogen Species	Human
Alternative Names	AUTS9 antibody, c met antibody, D249 antibody, Hepatocyte growth factor receptor antibody, HGF antibody, HGFR antibody, MET antibody, Met proto oncogene tyrosine kinase antibody, MET_HUMAN antibody, Oncogene MET antibody, Par4 antibody, Proto-oncogene c-Met antibody, RCCP2 antibody, Scatter factor receptor antibody, SF receptor antibody, Tyrosine-protein kinase Met antibody
Antigen	Met
Categories	Antibodies
Cellular Localization	Membrane
Certificate Of Analysis	A 1:250 dilution of SPC-1021 was sufficient for detection of Met (pThr1241) in 10 ug of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human Met (pThr1241) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Thr1241 of human Met (AA1237-1244), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Thr1241 of human Met (AA1237-1244)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Expressed in normal hepatocytes as well as in epithelial cells lining the stomach, the small and the large intestine. Found also in basal keratinocytes of esophagus and skin. High levels are found in liver, gastrointestinal tract, thyroid and kidney. Also present in the brain.

Swissprot	P08581
Accession Number	NP_000236
Gene Id	4233
Target	Met (pThr1241)
Research Area	Cell Signaling, Protein Phosphorylation, Tyrosine Kinases, Receptor Tyrosine Kinases, Cancer, Tumor Biomarkers, Oncoproteins, Growth Factor Receptors

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed in normal hepatocytes as well as in epithelial cells lining the stomach, the small and the large intestine. Found also in basal keratinocytes of esophagus and skin. High levels are found in liver, gastrointestinal tract, thyroid and kidney. Also present in the brain.
Scientific Background	MET is a receptor-tyrosine kinase that is activated upon binding hepatocyte growth factor (HGF). MET/HGF signalling has been implicated in the generation and progression of a variety of tumours. The coexpression of wild type MET and HGF in the same cell (which generates an autocrine stimulatory loop) induces oncogenic transformation. All investigated naturally occurring MET mutants show increased tyrosine phosphorylation level and enhanced kinase activity
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 155.527 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11913194-1	SPC-1021D	Unconjugated	100 ul	$331	Add to Cart
BHA11913194-2	SPC-1021D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11913194-3	SPC-1021D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11913194-4	SPC-1021D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11913194-5	SPC-1021D-BI	Biotin	100 ul	$380	Add to Cart
BHA11913194-6	SPC-1021D-FITC	FITC	100 ul	$375	Add to Cart

Met Antibody (pThr1241) - SPC-1021

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