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Home / Primary Antibodies

MED27 Antibody

SKU : BHA10558789

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA568842
Alternative Names	Cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation; subunit 8 (34kD); cofactor required for Sp1 transcriptional activation; subunit 8
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Humphray S.J., Nature 429:369-374(2004).The MGC Project Team, Genome Res. 14:2121-2127(2004).Ryu S., Nature 397:446-450(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human MED27.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Humphray S.J., Nature 429:369-374(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004). Ryu S., Nature 397:446-450(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MED27 protein.
Subcellular Location	Nucleus

Uniprot	Q6P2C8
Database Links	HGNC:2377 OMIM:605044 KEGG:hsa:9442 STRING:9606.ENSP00000292035 UniGene:Hs.374262
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Families	Mediator complex subunit 27 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558789	CSB-PA568842	100ul	$297		Add to Cart

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