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Home / Antibodies

MED24 Antibody

SKU : BHA10559250

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA177132
Alternative Names	100 kDa thyroid hormone receptor associated protein; ARC100; Activator-recruited cofactor 100 kDa component; DRIP100; KIAA0130
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).Rachez C., Genes Dev. 12:1787-1800(1998).Nagase T., DNA Res. 2:167-174(1995).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MED24.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998). Rachez C., Genes Dev. 12:1787-1800(1998). Nagase T., DNA Res. 2:167-174(1995).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MED24 protein.
Subcellular Location	Nucleus

Uniprot	O75448
Database Links	HGNC:22963 OMIM:607000 KEGG:hsa:9862 STRING:9606.ENSP00000377686 UniGene:Hs.462983
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Families	Mediator complex subunit 24 family
Tissue Specificity	Ubiquitous. Abundant in skeletal muscle, heart and placenta.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559250	CSB-PA177132	100ul	$297		Add to Cart

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