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Home / Antibodies

MED18 Antibody

SKU : BHA10558478

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA275975
Alternative Names	FLJ20045; mediator 18; mediator of RNA polymerase II transcription 18; p28b;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Furumoto T., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441:315-321(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MED18.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Furumoto T., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. Gregory S.G., Nature 441:315-321(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MED18 protein.
Subcellular Location	Nucleus

Uniprot	Q9BUE0
Database Links	HGNC:25944 OMIM:612384 KEGG:hsa:54797 STRING:9606.ENSP00000362948 UniGene:Hs.479911
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Families	Mediator complex subunit 18 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558478	CSB-PA275975	100ul	$297		Add to Cart

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