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Home / Primary Antibodies

ME1 Antibody

SKU : BHA10558527

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA597057
Alternative Names	NADP-dependent malic enzyme; EC 1.1.1.40; NADP-ME; Malic enzyme 1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.Loeber G., FEBS Lett. 344:181-186(1994).Gonzalez-Manchon C., Gene 159:255-260(1995).Totoki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human ME1.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Loeber G., FEBS Lett. 344:181-186(1994). Gonzalez-Manchon C., Gene 159:255-260(1995). Totoki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total ME1 protein.
Subcellular Location	Cytoplasm

Uniprot	P48163
Database Links	HGNC:6983 OMIM:154250 KEGG:hsa:4199 STRING:9606.ENSP00000358719 UniGene:Hs.21160
Pathway	PPAR signaling pathway
Protein Families	Malic enzymes family
Tissue Specificity	Expressed in all tissues tested including liver, placenta and white adipose tissue.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558527	CSB-PA597057	100ul	$297		Add to Cart

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