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Home / Primary Antibodies

MDM2 Antibody (V7950SAF)

SKU : BHA17127084

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NSJ Bioreagents

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Mfr.No.	V7950SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Amino acids 154-167 were used as the immunogen for the MDM2 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	Q00987

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the MDM2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA, WB, IHC-P
Description	ELISA (order BSA-free format for coating),Weste blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/mdm2-antibody-smp14-v7950" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127084	V7950SAF-100UG	100 ug	$499		Add to Cart

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