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Home / Antibodies

MCC Antibody / Mutated in Colorectal Cancers (RQ6655)

SKU : BHA17119069

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NSJ Bioreagents

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Mfr.No.	RQ6655
Antigen	MCC
Clonality	Polyclonal (rabbit origin)
Description	MUTATED IN COLORECTAL CANCERS (MCC) is a tumor suppressor gene. It is mapped to 5q22.2. This gene suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. MCC also Inhibits DNA binding of b-catenin/TCF/LEF transcription factors, and it is Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation. What's more, MCC can interact with SCRIB (via phosphorylated PDZ-binding motif), EZR, SNX27, SLC9A3R1 and SLC9A3R2.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids M1-E234) was used as the immunogen for the Mutated in Colorectal Cancers antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	P23508

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the Mutated in Colorectal Cancers antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, FACS, Direct ELISA
Dilution	Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119069	RQ6655	100ug	$419		Add to Cart

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