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Home / Primary Antibodies

MC3R Antibody

SKU : BHA10558922

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA261897
Alternative Names	MC3; OB20; OQTL; BMIQ9; MC3-R
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to residues near the N terminal of Human melanocortin 3 receptor
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MC3R protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	P41968
Database Links	HGNC:6931 OMIM:155540 KEGG:hsa:4159 STRING:9606.ENSP00000243911 UniGene:Hs.248018
Function	Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
Protein Families	G-protein coupled receptor 1 family
Tissue Specificity	Brain, placental, and gut tissues.

Buffer	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Format	liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558922	CSB-PA261897	100ul	$297		Add to Cart

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