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Home / Primary Antibodies

MBL2 Antibody

SKU : BHA10558477

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA127636
Alternative Names	Mannose-binding protein C; MBP-C; MBP1; Mannan-binding protein; Mannose-binding lectin
Categories	Primary Antibodies
Clonality	polyclonal
Description	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988).Sastry K., J. Exp. Med. 170:1175-1189(1989).Taylor M.E., Biochem. J. 262:763-771(1989).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MBL2.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988). Sastry K., J. Exp. Med. 170:1175-1189(1989). Taylor M.E., Biochem. J. 262:763-771(1989).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MBL2 protein.
Subcellular Location	Secreted

Uniprot	P11226
Database Links	HGNC:6922 OMIM:154545 KEGG:hsa:4153 STRING:9606.ENSP00000363079 UniGene:Hs.499674
Function	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Pathway	Complement and coagulation cascades
Tissue Specificity	Plasma protein produced mainly in the liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558477	CSB-PA127636	100ul	$297		Add to Cart

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