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Home / Primary Antibodies

MAZ Antibody

SKU : BHA10558506

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA148200
Alternative Names	Myc-associated zinc finger protein; MAZI; Purine-binding transcription factor; Pur-1; ZF87
Categories	Primary Antibodies
Clonality	polyclonal
Description	May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.Bossone S.A., Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).Pyrc J.J., Biochemistry 31:4102-4110(1992).Tsutsui H., Biochem. Biophys. Res. Commun. 226:801-809(1996).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MAZ.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins. Bossone S.A., Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992). Pyrc J.J., Biochemistry 31:4102-4110(1992). Tsutsui H., Biochem. Biophys. Res. Commun. 226:801-809(1996).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MAZ protein.
Subcellular Location	Nucleus

Uniprot	P56270
Database Links	HGNC:6914 OMIM:600999 KEGG:hsa:4150 STRING:9606.ENSP00000219782 UniGene:Hs.23650
Function	May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Tissue Specificity	Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558506	CSB-PA148200	100ul	$297		Add to Cart

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