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Home / Antibodies

MATK Antibody

SKU : BHA10558868

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA220699
Alternative Names	CHK; Csk-homologous kinase; Csk-type protein tyrosine kinase; CTK; DKFZp434N1212
Categories	Primary Antibodies
Clonality	polyclonal
Description	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.Sakano S., Oncogene 9:1155-1161(1994).Bennett B.D., J. Biol. Chem. 269:1068-1074(1994).Avraham S., J. Biol. Chem. 270:1833-1842(1995).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human MATK.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. Sakano S., Oncogene 9:1155-1161(1994). Bennett B.D., J. Biol. Chem. 269:1068-1074(1994). Avraham S., J. Biol. Chem. 270:1833-1842(1995).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MATK protein.
Subcellular Location	Cytoplasm, Membrane

Uniprot	P42679
Database Links	HGNC:6906 OMIM:600038 KEGG:hsa:4145 STRING:9606.ENSP00000378485 UniGene:Hs.631845
Function	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Pathway	Neurotrophin signaling pathway
Protein Families	Protein kinase superfamily, Tyr protein kinase family, CSK subfamily
Tissue Specificity	Expressed in various myeloid cell lines, detected in brain and lung.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558868	CSB-PA220699	100ul	$297		Add to Cart

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