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Home / Antibodies

MASP2 Antibody

SKU : BHA10558476

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA943074
Alternative Names	Mannan-binding lectin serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2; MBL-associated serine protease 2;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.Thiel S., Nature 386:506-510(1997).Takahashi M., Int. Immunol. 11:859-863(1999).Stover C.M., J. Immunol. 162:3481-3490(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human MASP2.
Involvement In Disease	MASP2 deficiency (MASPD)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. Thiel S., Nature 386:506-510(1997). Takahashi M., Int. Immunol. 11:859-863(1999). Stover C.M., J. Immunol. 162:3481-3490(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total MASP2 protein.
Subcellular Location	Secreted

Uniprot	O00187
Database Links	HGNC:6902 OMIM:605102 KEGG:hsa:10747 STRING:9606.ENSP00000383690 UniGene:Hs.655645
Function	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Pathway	Complement and coagulation cascades
Protein Families	Peptidase S1 family
Tissue Specificity	Plasma.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558476	CSB-PA943074	100ul	$297		Add to Cart

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