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Home / Primary Antibodies

MAPK6 Antibody

SKU : BHA10559327

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA073951
Alternative Names	Mitogen-activated protein kinase 6; EC 2.7.11.24; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97
Categories	Primary Antibodies
Clonality	polyclonal
Description	Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle By similarity.Zhu A.X., Mol. Cell. Biol. 14:8202-8211(1994).Meloche S., Oncogene 13:1575-1579(1996).The MGC Project Team, Genome Res. 14:2121-2127(2004)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human p97 MAPK.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle By similarity. Zhu A.X., Mol. Cell. Biol. 14:8202-8211(1994). Meloche S., Oncogene 13:1575-1579(1996). The MGC Project Team, Genome Res. 14:2121-2127(2004)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total p97 MAPK protein.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	Q16659
Database Links	HGNC:6879 OMIM:602904 KEGG:hsa:5597 STRING:9606.ENSP00000261845 UniGene:Hs.411847
Function	Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events
Pathway	IL-17 signaling pathway
Protein Families	Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
Tissue Specificity	Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559327	CSB-PA073951	100ul	$297		Add to Cart

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