Caught by MAD2 protein; CMT2; KIAA0110; MAD2L1 binding protein; MAD2L1-binding protein
Categories
Primary Antibodies
Clonality
polyclonal
Description
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.Nagase T., DNA Res. 2:37-43(1995).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Mungall A.J., Nature 425:805-811(2003).
Host
Rabbit
Immunogen
Synthesized peptide derived from N-terminal of Human MAD2L1BP.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Nagase T., DNA Res. 2:37-43(1995). Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Mungall A.J., Nature 425:805-811(2003).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total MAD2L1BP protein.
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Protein Families
MAD2L1BP family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.