Macrophage Colony Stimulating Factor 1, also called MCSF or CSF1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. MCSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of MCSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or MCSFR encoded by the c-fms proto-oncogene), MCSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids 33-262 of mouse Colony stimulating factor 1 were used as the immunogen for the Csf-1 antibody.
Isotype
IgG
Predicted Reactivity
Mouse, Rat
Reactivity
Mouse, Rat
Recombinant
No
Subcellular Location
Cytoplasmic, membrane
Uniprot
P07141
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the Csf-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.