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Home / Primary Antibodies

LYVE1 Antibody

SKU : BHA10557497

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA566878
Alternative Names	LYVE1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Heindl LM, et al. (2010) Ophthalmology.117(2):334-42.He P et al.(2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi.20(18):828-30, 833.Lim HY,et al. (2009) Am J Pathol.175(3):1328-37.
Host	Rabbit
Immunogen	Peptide sequence around aa.271~275 (K-N-Q-Q-K) derived from Human Lymphatic vessel endothelial hyaluronic acid receptor 1.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Heindl LM, et al. (2010) Ophthalmology.117(2):334-42. He P et al.(2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi.20(18):828-30, 833. Lim HY,et al. (2009) Am J Pathol.175(3):1328-37.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total Lymphatic vessel endothelial hyaluronic acid receptor 1 protein.
Subcellular Location	Membrane, Single-pass type I membrane protein

Uniprot	Q9Y5Y7
Database Links	HGNC:14687 OMIM:605702 KEGG:hsa:10894 STRING:9606.ENSP00000256178 UniGene:Hs.655332
Function	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Tissue Specificity	Mainly expressed in endothelial cells lining lymphatic vessels.

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557497	CSB-PA566878	100ul	$297		Add to Cart

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