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Home / Primary Antibodies

Luteinizing Hormone alpha Antibody / hCG alpha (V3277SAF)

SKU : BHA17124931

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NSJ Bioreagents

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Mfr.No.	V3277SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This mAb reacts with a protein of ~13kDa, identified as alpha subunit of Luteinizing Hormone (LH) or Chorionic Gonadotrophin (CG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties. LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Recombinant full-length human LHa protein was used as the immunogen for the Luteinizing Hormone alpha antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the Luteinizing Hormone alpha antibody should be determined by the researcher.

Uniprot	P01215

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Luteinizing Hormone alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (HIER is not recommended for this antibody)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17124931	V3277SAF-100UG	100 ug	$499		Add to Cart

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