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Home / Antibodies

LSP1 Antibody / Lymphocyte Specific Protein 1 (V7929SAF)

SKU : BHA17127067

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NSJ Bioreagents

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Mfr.No.	V7929SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant human partial protein (amino acids 174-278) was used as the immunogen for this LSP1 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P33241

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the LSP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/lsp1-antibody-lsp1-3042-v7929" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127067	V7929SAF-100UG	100 ug	$499		Add to Cart

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