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Home / Antibodies

LILRB4 Antibody

SKU : BHA10558462

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA297929
Alternative Names	Leukocyte immunoglobulin-like receptor subfamily B member 4 ; Leukocyte immunoglobulin-like receptor 5; LIR-5; Immunoglobulin-like transcript 3; ILT-3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.Arm J.P., J. Immunol. 159:2342-2349(1997). Borges L., J. Immunol. 159:5192-5196(1997). Liu W.R., Immunogenetics 51:659-669(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human LILRB4.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. Arm J.P., J. Immunol. 159:2342-2349(1997). Borges L., J. Immunol. 159:5192-5196(1997). Liu W.R., Immunogenetics 51:659-669(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total LILRB4 protein.
Subcellular Location	Cell membrane, Single-pass type I membrane protein

Uniprot	Q8NHJ6
Database Links	HGNC:6608 OMIM:604821 KEGG:hsa:11006 STRING:9606.ENSP00000270452 UniGene:Hs.67846
Function	Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Pathway	Osteoclast differentiation
Tissue Specificity	Detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF

Description

ELISA ; IF, IF ; ELISA

Dilution

IF	1:100-1:500

Tested Application

ELISA,IF;IF:1:100-1:500

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558462	CSB-PA297929	100ul	$297		Add to Cart

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