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Home / Antibodies

LILRB1 Antibody / ILT-2 (V8530SAF)

SKU : BHA17127572

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NSJ Bioreagents

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Mfr.No.	V8530SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. Immunoglobulin-like transcript 2 (ILT-2), also known as CD85 or MIR7, is a 650 amino acid glycoprotein that contains a 23 amino acid signal peptide, 4 extracellular C2-type IGSF domains and 4 intracellular ITIM motifs. ILT-2 can bind major histocompatability (MHC) class I molecules and inhibit cell termination by natural killer (NK) and T cells, and inhibit Ca2+ mobilization in myeloid cells triggered through the B cell antigen receptor and histocompatibility leukocyte antigens (HLA)-DR. ILT-2 contains four putative cytoplasmic tyrosine-based inhibitory motifs and upon tyrosine phosphorylation, associates with the tyrosine phosphatase SHP-1.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Hairy cell leukemia cells were used as the immunogen for the LILRB1 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the LILRB1 antibody should be determined by the researcher.

Uniprot	Q8NHL6

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the LILRB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IP, WB, FACS
Description	Immunoprecipitation: 1-2ug per 100-500ug of total protein (1ml of cell lysate),Weste blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/lilrb1-antibody-vmp55-v8530" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127572	V8530SAF-100UG	100 ug	$499		Add to Cart

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