Low-density lipoprotein receptor class A domain-containing protein 3;
Categories
Primary Antibodies
Clonality
polyclonal
Description
May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production By similarity.Otsuki T., DNA Res. 12:117-126(2005).The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human LDLRAD3.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production By similarity.
Otsuki T., DNA Res. 12:117-126(2005). The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LDLRAD3 protein.
Subcellular Location
Cell membrane, Single-pass type I membrane protein
May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production.
Protein Families
LDLR family
Tissue Specificity
Expressed at high levels in brain, lung, skeletal muscle, and pancreas. Expressed at moderate levels in heart, placenta, and kidney but not detected in the liver.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.