MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by MAP1LC3A (microtubule associated protein 1 light chain 3 alpha) is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for MAP1LC3A. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Clonality
Monoclonal
Description
Mouse Anti-LC3A Mouse Monoclonal Antibody (5G10)
Formulation
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host
Mouse
Immunogen
Synthetic Peptide of LC3A
Immunogen Region
Synthetic Peptide of LC3A
Isotype
Mouse IgG1
Molecular Weight
14, 16 KD
Others
LC3A protein detects endogenous levels of LC3A.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity
Human, Mouse, Rat
Tag
LC3A
Note
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IF (1:100-1:200), IHC-P (1:100-1:200).
Accession Number
Q9H492
Gene Id
84557, 84557
Concentration
1 mg/ml, 1 mg/ml
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.