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Home / Antibodies

LC3A/B Antibody (F54060)

SKU : BHA17119955

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NSJ Bioreagents

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Mfr.No.	F54060-0.1ML
Clonality	Monoclonal (mouse origin)
Description	LC3A:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. (UniProt)LC3B:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. (UniProt)
Formulation	Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host	Mouse
Immunogen Region	A synthetic LC3B peptide was used as the immunogen for this LC3A/B antibody.
Isotype	Mouse IgG2b
Species Reactivity	Human, Rat
Note	The stated application concentrations are suggested starting points. Titration of the LC3A/B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q9H492, Q9GZQ8

Format	Purified
Purity	Protein G affinity
Storage	Store the LC3A/B antibody at -20oC.

Applications	WB
Description	Weste blot: 1:1000

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119955	F54060-0.1ML	0.1 ml	$379		Add to Cart

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