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Home / Antibodies

LARGE Antibody / Like acetylglucosaminyltransferase

SKU : BHA17102504

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NSJ Bioreagents

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Mfr.No.	F53896
Clonality	Polyclonal
Description	Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units (-3-Xylose-alpha-1,3-GlcA-beta-1-) to produce a heteropolysaccharide.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 365-398 from the human protein was used as the immunogen for the LARGE antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	O95461
Gene Id	9215

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the LARGE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Weste blot: 1:1000-2000

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102504	F53896	0.05 ml	$155		Add to Cart

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