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Home / Primary Antibodies

LARGE Antibody / Like acetylglucosaminyltransferase (F53896)

SKU : BHA17119884

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NSJ Bioreagents

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Mfr.No.	F53896-0.05ML
Clonality	Polyclonal (rabbit origin)
Description	Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units (-3-Xylose-alpha-1,3-GlcA-beta-1-) to produce a heteropolysaccharide.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 365-398 from the human protein was used as the immunogen for the LARGE antibody.
Isotype	Rabbit Ig
Species Reactivity	Human

Uniprot	O95461

Format	Antigen affinity purified
Purity	Antigen affinity
Storage	Aliquot the LARGE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot: 1:1000-2000

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119884	F53896-0.05ML	0.05 ml	$165		Add to Cart

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