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Home / Primary Antibodies

L1CAM Antibody / NCAM-L1 / CD171 (V8835SAF)

SKU : BHA17122890

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NSJ Bioreagents

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Mfr.No.	V8835SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Homogenous suspension of 16-week human fetal brain cells were used as the immunogen for the L1CAM antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the L1CAM antibody should be determined by the researcher.

Uniprot	P32004

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122890	V8835SAF-100UG	100ug	$499		Add to Cart

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