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Home / Primary Antibodies

L1CAM Antibody / NCAM-L1 / CD171 (V2182SAF)

SKU : BHA17123543

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NSJ Bioreagents

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Mfr.No.	V2182SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	This antibody recognizes a cell surface protein of 220-240kDa, identified as L1CAM (L1 cell adhesion molecule). The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). L1CAM also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. antibody to L1CAM is useful in the identification of primitive neuroectodermal tumors. The antibody binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A homogenous suspension of 16 week human fetal brain was used as the immunogen for this L1CAM antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Uniprot	P32004

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the L1CAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA/sodium azide-free format for coating)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17123543	V2182SAF-100UG	100 ug	$499		Add to Cart

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