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Home / Antibodies

Ku80 Antibody / XRCC5 (V8929SAF)

SKU : BHA17122964

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NSJ Bioreagents

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Mfr.No.	V8929SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 or (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Ku has several functions, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity; serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 300-500 was used as the immunogen for the XRCC5/Ku80 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the XRCC5/Ku80 antibody should be determined by the researcher.

Uniprot	P13010

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the XRCC5/Ku80 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122964	V8929SAF-100UG	100ug	$499		Add to Cart

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