Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Sarcolectin (SCL): structure and expression of the recombinant molecule."Kaba A., Jiang P., Chany-Fournier F. Biochimie 81:709-715(1999) "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7."Lin L., Holbro T., Alonso G. J. Cell. Biochem. 80:483-490(2001) "Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit a(1)-globin and human cytokeratin 7."Kanduc D. J. Virol. 76:7040-7048(2002)"
Host
Rabbit
Immunogen
Peptide sequence around aa.22~26(A-Q-V-R-L) derived from Human Keratin 7
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Sarcolectin (SCL): structure and expression of the recombinant molecule."
Kaba A., Jiang P., Chany-Fournier F. Biochimie 81:709-715(1999) "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7." Lin L., Holbro T., Alonso G. J. Cell. Biochem. 80:483-490(2001) "Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit a(1)-globin and human cytokeratin 7." Kanduc D. J. Virol. 76:7040-7048(2002)"
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Keratin 7 protein.
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Protein Families
Intermediate filament family
Tissue Specificity
Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.